Thresholds and Endocrine Disruptors: An Endocrine Society Policy Perspective

Endocrine Policy Forum Endocrine Policy Forum Frequently Asked Questions about Endocrine Disruptors General Background on Endocrine Disruption

Why all the talk about endocrine disruptors? In response to public concern that certain environmental chemicals may interfere with endocrine processes in humans, the U.S. Congress passed the Food Quality Protection Act and amendments to the Safe Drinking Water Act in 1996. These laws directed the US EPA to develop and implement a program to investigate the potential for substances to cause adve...

Endocrine Disruptors

Law and science combine in the estimation of risks from endocrine disruptors (EDs) and actions for their regulation. For both, dose–response models are the causal link between exposure and probability (or percentage change) of adverse response. The evidence that leads to either regulations or judicial decrees is affected by uncertainty and limited knowledge, raising difficult policy issues that...

Essential Medicines for Children: An Endocrine Perspective

Endocrine Disruptors and Obesity

PURPOSE OF REVIEW The purpose of this review was to summarise current evidence that some environmental chemicals may be able to interfere in the endocrine regulation of energy metabolism and adipose tissue structure. RECENT FINDINGS Recent findings demonstrate that such endocrine-disrupting chemicals, termed "obesogens", can promote adipogenesis and cause weight gain. This includes compounds ...

Endocrine disruptors: from endocrine to metabolic disruption.

Synthetic chemicals currently used in a variety of industrial and agricultural applications are leading to widespread contamination of the environment. Even though the intended uses of pesticides, plasticizers, antimicrobials, and flame retardants are beneficial, effects on human health are a global concern. These so-called endocrine-disrupting chemicals (EDCs) can disrupt hormonal balance and ...